Specificity of Complete Cold Auto-Agglutinins
نویسندگان
چکیده
منابع مشابه
Platelet cold agglutinins.
A “cold” platelet agglutinin is described reacts only at temperatures below 34#{176}C. which is present in plasma and serum, It agglutinates homologous and autois greater than 100,000 in molecular logous platelets but appears to have no weight, appears to be a protein of the imeffect on in vivo platelet function. It is munoglobulin type, is adsorbed by plateseen in patients with systemic diseas...
متن کاملSpecificity of Agglutinins and Precipitins
The knowledge of serological reactions has opened a field of research dealing with the specific configurations existing in the chemical constituents of organisms. The results of agglutinin and lysin reactions and the use of the absorption method have disclosed an unexpected variety of structures as exemplified by the existence of differently reacting groups in a single kind of cells, of differe...
متن کاملHow I manage cold agglutinins.
From the Department of Pathology, University of Michigan Medical Center, Ann Arbor, Michigan. Address reprint requests to: W. John Judd, FIBMS, MIBiol, Professor of Immunohematology, Department of Pathology, UH-2G332, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0054; e-mail: [email protected]. Received for publication November 2, 2005; accepted No...
متن کاملThe in vivo metabolism of radioiodinated cold agglutinins of anti-I specificity.
1. The metabolism of six purified and radioiodinated cold agglutinins has been studied in five patients with chronic cold haemagglutinin disease and in six normal controls. Two of the patients showed overt haemolysis at the time of this study and all had complement components adsorbed to the surface of their red cells. 2. The mean fractional catabolic rate (FCR) of the cold agglutinins, studied...
متن کاملExperimental Production of Cold Agglutinins in Rabbits.
By NICoi S COSTEA, VINCENT YAKULLS AND PAUL HELLER H EMOLYTIC ANEMIA of the cold agglutinin ( CA ) variety is believed to represent an autoimmune disorder occasionally complicating the course of lymphoproliferative diseases.’2 Whereas animal models have been proposed for the investigation of various autoimmune phenomena,3 cold reacting erythrocyte autoantibodies have not yet been studied in exp...
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ژورنال
عنوان ژورنال: Nature
سال: 1953
ISSN: 0028-0836,1476-4687
DOI: 10.1038/172734a0